The Statewide Prosecution Bureau is responsible for the investigation and prosecution of "white collar" crimes, including government corruption. Program areas include criminal violations of the environmental protection laws, government corruption and other offenses against public integrity. 

The LeRoy Brown, Jr. and Karen Clarke Witness Protection Program operates under the Statewide Prosecution Bureau in cooperation with the State's Attorneys and local, state and federal law enforcement agencies to identify and protect witnesses in criminal proceedings where there is evidence of substantial danger that the witness may suffer from intimidation or retaliatory violence. The unit was formally created in 1999 with the enactment of Public Act 99-240, which established the Leroy Brown, Jr. and Karen Clarke Witness Protection Program.

Through a variety of means, tailored to the individual circumstances presented by each witness, the Witness Protection Unit coordinates protection both to protect their safety and the interest of justice. Services can include temporary relocation, semi-permanent relocation in or outside of Connecticut and police protection. The Unit provides some form of assistance to approximately 200 individuals each year.