From Groton/Mystic/ New London*
Follow I-95 south to Route 32 to I-395. Take Exit 80 east. (travel time 15 minutes)

From Colchester and points West:*
Follow Route 2 east until it merges with Route 32 south. Take Exit 28S onto I-395 south to Exit 80. Take a left at the end of the Exit ramp (Route 82 West Main Street). (travel time 23 minutes)

From Jewett City and points North*
Take I-395 south to Exit 80. Take a left at the end of the Exit ramp (Route 82 West Main Street). (travel time 20 minutes)

From Ledyard/Navy Sub Base area:*
Follow 2A (Mohegan Pequot Bridge) to I-395 north. Take Exit 80 east. (travel time 25 minutes)

From New Haven and points south*
Take I-95 north to I-395 north (exit 76). Take I-395 north to Exit 80 east.

*From all points above:
Go five lights down to New London Turnpike. Turn right. Thames Valley campus is about .2 miles on left.